.Nature Medication, Published online: 18 September 2024 doi:10.1038/ s41591-024-03300-3Genomic and also epidemiologic analyses revealed that an unfamiliar reassortant popular descent of the Oropouche infection, which has been flowing in the western Amazon.com area of Brazil for concerning a decade, is related to the recent individual outbreaks between 2022 and 2024.