.Writers as well as AffiliationsDana-Farber Cancer Cells Institute, Brigham and Womenu00e2 $ s Hospital and Harvard Medical School, Boston Ma, MA, USAToni K. Choueiriu00c2 & u00c2 William G. Kaelin JrHoward Hughes Medical Principle, Chevy Pursuit, MD, USAWilliam G. Kaelin JrCorresponding authorsCorrespondence to.Toni K. Choueiri or William G. Kaelin Jr.